What do Michigan senator-elect Abdul El-Sayed, South Carolina senator-elect Annie Andrews, Ohio governor-elect Amy Acton, and North Carolina representative-elect Jamie Ager have in common, beyond their victories in this week’s midterm elections?
Each is either a doctor or a scientist. And each had the backing of the political action committee 314 Action Fund, which focuses on electing pro-science voices to public office.
“We really benefit by having those data-driven, fact-based decisionmakers actually in a position at the governing table,” says Shaughnessy Naughton, a chemist and former congressional candidate who founded 314 Action after losing her race in 2016. This cycle, the PAC spent above $30 million donating to and supporting various campaigns, including fundraising for specific races. It raised $3.6 million for pediatrician Andrews in the fight over what had been Lindsay Graham’s Senate seat in South Carolina, for example, and another $3 million for physician Acton’s campaign in the hotly contested Ohio governor race, according to Naughton.
The organization’s success rate topped 80 percent this cycle for congressional candidates, with 14 of 17 of its candidates in the US House of Representatives winning their races and hundreds of successful down-ballot candidates. Nine of these races flipped seats from Republican to Democrat. Victorious congressional candidates who flipped their districts this year include an oncology nurse-practitioner, a mathematician, a microbiologist, a nuclear engineer, and an agricultural scientist. “It did turn out to be a health care election,” Naughton says.
Richard Frank, the director of the Brookings Institute’s Center on Health Policy, notes that health care workers and scientists have always been part of the makeup of Congress, but not to this degree. “What is unusual,” he says, “is just how many came in one wave.” He sees the spike in this type of candidate as a direct result of the hostility toward medical and technical expertise from the Trump administration. “Science has been under attack,” Frank says. “It’s not surprising that scientists have recognized that, and some of them went out and ran for Congress.”
The rise of the science candidate has several causes, according to historian Kristoffer Shields, who runs Rutgers University’s Eagleton Institute of Politics. “Some of it certainly is a reaction to what's been happening at the federal level, the defunding of a lot of laboratories and scientific exploration,” he says. But he also sees this as a legacy of the pandemic, when many health care workers started thinking about how politics impacts public health.
Earlier this year, El-Sayed emphasized to WIRED that his candidacy was focused on public health, noting that the cyclospora outbreak that sickened Americans over the summer likely stemmed from the Trump administration’s choices. “We DOGE’d our whole service that keeps the lettuce safe,” he said at the time, referencing the so-called Department of Government Efficiency directing mass layoffs at the Food and Drug Administration.
In 2024, 314 Action’s past acceptance of funding from groups with ties to the pro-Israel lobbying group AIPAC came under scrutiny. The organization no longer accepts AIPAC funding and supported candidates like El-Sayed who were vocally critical of the Israeli government. Unlike some other political committees that aim to put doctors in office, like the American Medical Association’s PAC, 314 Action specifically focuses on electing Democratic health and science experts; it is forthright about its opposition to the Trump administration’s approach to public health.
That so many of these politicians are advocates for the importance of public health and scientific expertise suggests that the election was, in part, a rejection of current health secretary Robert F. Kennedy Jr.’s MAHA movement, which promotes medical misinformation, including anti-vaccine sentiment. Many of the winning candidates with scientific and technical backgrounds have explicitly discussed how their concerns about the state of health care policy drove them to enter the race. “I am appalled seeing infectious diseases spreading through our communities that we had once declared eradicated,” microbiologist Jasmine Clark, the incoming representative from Georgia, told The Guardian earlier this year.
Clark was first supported by 314 Action when she ran for Georgia’s House of Representatives eight years ago. “She was in the first class of scientists that we helped elect in that 2018 cycle and now has made that move up to the federal level,” says Naughton.
Shields sees the straightforward communication style favored by doctors and scientists as another asset that has made them strong candidates. Some of this year’s winners are especially direct. In recent interviews, South Carolina’s Annie Andrews has referred to RFK Jr. as her “archnemesis” and promised to hold him accountable.
314 Action has also been clear that rebuking RFK Jr.’s agenda is a core part of its goals. In 2025, it launched its Guardians of Public Health initiative to recruit health care experts to run for public office. “We thought it was important to speak directly to doctors and people in public health, like nurses, to say that we have this program and we need you to step up to run, because we have a madman running the Health and Human Services cabinet,” Naughton says.
The push for pro-science public servants isn’t over; 314 Action is starting its next recruitment round later this month.
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